DURHAM, N.C. — The Pediatric Brain Tumor Foundation (PBTF) is giving $6 million to its research institute at Duke University to further the work… (Source: dukehealth.org: Duke Health News)
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(Source: Clinical Trials And Noteworthy Treatments For Brain Tumors)
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Present trend in the primary treatment of aggressive malignant glioma: glioblastoma multiforme.
Technol Cancer Res Treat. 2008 Jun;7(3):241-8
Authors: Parvez T
The standard treatment for glioblastoma multiforme is surgery, radiation, and chemotherapy. Yet this aggressive therapy has only a modest effect on survival with most patients surviving less than 1 year after diagnosis. This poor prognosis has lead scientists to seek alternative molecular approaches for the treatment of glioblastoma multiforme. Among these, gene therapy, vaccine therapy, and immunotherapy are all approaches that are currently being investigated. While these molecular approaches may not herald an immediate change in the prognosis of these aggressive tumors, combining them with existing approaches may bring some progress in the standard of care. This paper reviews current treatments and several newer therapies in preclinical and early clinical studies.
PMID: 18473496 [PubMed - in process]
(Source: Technology in Cancer Research and Treatment)
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Expert Opinion on Biological Therapy , June 2008, Vol. 8, No. 6, Pages 805-812. Background: Interleukin-13 (IL-13) receptors are overexpressed in glioblastoma multiforme (GBM). The presence of IL-13 binding sites in GBM and their absence in normal brain tissue validates IL-13 receptor as an important target in human GBM. Objective: … (Source: Expert Opinion: Expert Opinion on Biological Therapy: Table of Contents)
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(Source: Clinical Trials And Noteworthy Treatments For Brain Tumors)
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A veterinary neurologist on faculty in the Virginia-Maryland Regional College of Veterinary Medicine(http://www.vetmed.vt.edu/) at Virginia Tech has been awarded funding from the Wake Forest University Translational Science Institute to study innovative approaches for treating brain tumors in dogs, cats and humans.Dr. (Source: Veterinary News From Medical News Today)
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Page: 493DOI: 10.1227/01.neu.0000316018.51292.19Authors: Kobayashi, Keiichi M.D., Ph.D.; Ohnishi, Akiko M.D., Ph.D.; Promsuk, Jutabha Ph.D.; Shimizu, Saki B.S.; Kanai, Yoshikatsu Ph.D.; Shiokawa, Yoshiaki M.D., Ph.D.; Nagane, Motoo M.D., Ph.D. (Source: Neurosurgery)
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(Source: Clinical Trials And Noteworthy Treatments For Brain Tumors)
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Page: 505DOI: 10.1227/01.neu.0000316019.28421.95Authors: Ogden, Alfred T. M.D. *; Waziri, Allen E. M.D. *; Lochhead, Richard A. M.D.; Fusco, David B.A.; Lopez, Kim M.D.; Ellis, Jason A. B.A., M.S.; Kang, Joann B.A.; Assanah, Marcela Ph.D.; McKhann, Guy M. M.D.; Sisti, Michael B. M.D.; McCormick, Paul C. M.D.; Canoll, Peter M.D., Ph.D. **; Bruce, Jeffrey N. M.D. ** (Source: Neurosurgery)
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